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CortiSLIM and the Stress Hormone Cortisol

The Nature of Cortisol

CortiSLIM is specifically formulated to help increase metabolism and normalize cortisol levels. Along with adrenaline and cortisone, excess cortisol is known as one of the stress hormones and is released in abundance during those times. Researchers from UC San Francisco validated that those with increased belly fat had higher levels of cortisol compared to others with less belly fat.

There are plenty of studies to at least suggest a link between central obesity; marked by abdominal fat and a high waist-to-hip ratio and elevated cortisol levels. New studies are produced every week making this correlation.

One such study examined 59 healthy premenopausal women, 30 of whom demonstrated central fat distribution as determined by a high waist-to-hip ratio, and 29 of whom did not. All 59 women participated in three sessions of psychosocial challenges on four consecutive days to gauge and measure their reaction to stress. Women with higher waist-to-hip ratios experienced the laboratory challenges as more threatening, performed more poorly on them, and reported more chronic stress. These women also secreted more cortisol than women with lower waist-to-hip ratios. The investigators noted that central fat distribution is related to greater psychological vulnerability to stress and cortisol reactivity. They then state; “stress-induced cortisol secretion may contribute to central fat.”

In a study published in 2004, researchers examined the relationship between stress levels, cortisol, and abdominal obesity in 22 obese women, 11 of whom had a binge-eating disorder. The researchers found a positive correlation between high stress and cortisol levels and central obesity, noting, “Hyperactive HPA axis due to stress raises cortisol levels which then may contribute to binge eating and abdominal obesity.”

Clearly, there is an intimate relationship between stress, cortisol levels, and overall health. Modulating cortisol levels may thus offer support for healthy weight management and prevent negative health outcomes associated with central obesity, such as type II diabetes.

Cortisol is a necessary hormone, but not unlike other hormones such a testosterone, progesterone, or estrogen, if cortisol is out of balance and in excess, it becomes toxic to the body. The key to CortiSLIM is its ability to bring cortisol back into balance while increasing ones metabolism, thus effectuating body fat accumulation, energy levels and more.

According to Nicholas V. Perricone, MD, “When we are under stress, our adrenal glands produce hormones. These include the fight-or-flight hormones, epinephrine (adrenaline) and norepinephrine (noradrenaline), as well as cortisol.

Cortisol is a glucocorticoid, one of a group of steroid hormones that include cortisone. Cortisol is involved in carbohydrate, protein, and fat metabolism, and has anti-inflammatory properties. As we age, the “youth” hormones such as testosterone, estrogen, and human growth hormone decline. Cortisol, however, increases as we age and too much cortisol can also become pro-inflammatory.

When we experience stress (whether from fear, anxiety, physical or emotional trauma, or overexertion), the stress hormones epinephrine and norepinephrine will return to normal levels as the stress subsides. In a young person, cortisol levels will also return to normal within a few hours. Because cortisol levels continue to rise with age, the older person’s cortisol levels will remain elevated for long periods of time. This has earned cortisol the dubious distinction of being known as a “death” hormone, because high levels of cortisol exert a catabolic or muscle-wasting, deteriorating action on the body. Simply put, it breaks down tissue.


Epel ES, McEwen B, Seeman T, et al. Stress and body shape: Stress-induced cortisol secretion is consistently greater among women with central fat. Psychosomatic Med. 2000 Sept; 62(5):623-32.


Gluck ME, Geliebter A, Lorence M. Cortisol stress response is positively correlated with central obesity in obese women with binge eating disorder (BED) before and after cognitive-behavioral treatment. Ann NY Acad Sci. 2004 Dec; 1032:202-7.